Periodontal treatment may reduce levels of systemic inflammation markers associated with atherosclerotic profile.

Key Study Factor The criteria for selecting the trials were as follows: (1) Human subjects with periodontitis; (2) intervention group receiving periodontal treatment (PT) and a non-intervention group receiving no periodontal treatment (NPT); and (3) outcome variables must be clinical CVD parameters and/or markers of atherosclerosis and CVD risk, including markers of systemic inflammation and thrombosis, lipid and glucose metabolism, and vascular function.